WELCOME
My name is Ashley Ingiosi, and I am a BRAIN Initiative K99/R00 investigator & Ruth L. Kirschstein postdoctoral fellow in the laboratory of Marcos Frank, PhD at Washington State University in Spokane. My current research focuses on the role of astrocytes in sleep and sleep homeostasis. I will continue this research as an Assistant Professor in the Department of Neuroscience at The Ohio State University beginning Fall 2022.
Interests
-
Sleep & Sleep Homeostasis
-
Astrocytes
-
Neuronal-glial interactions
-
Neuroinflammation
-
In vivo imaging
-
Autism
Education
PhD in Neuroscience, 2015
University of Michigan
BS in Biopsychology & Cognitive Science and General Biology, 2006
University of Michigan
A role for astroglial calcium in mammalian sleep and sleep regulation
Ingiosi AM, Hayworth CR, Harvey DO, Singletary KG, Rempe MJ, Wisor JP, Frank MG (2020) Current Biology 30:4373-4383.e7
Video shows astrocyte activity in the brain during non-rapid eye movement sleep (NREMS), rapid eye movement sleep (REMS) and wakefulness (WAKE) as captured with a genetically encoded calcium indicator and miniscope. Video shown is 16x faster than normal speed.
A quick discussion of our main findings can be found here.
News &
Announcements
Howard Hughes Medical Institute scholarship recipient for The Jackson Laboratory Impacts of Sleep and Circadian Biology on Alzheimer’s Disease and Aging workshop
Scholarship recipient for the American Academy of Sleep Medicine Foundation Young Investigators Research Forum 2021 cohort
Astrocytes, not just neurons, play a role in sleep
The Scientist
Our study exploring the role of astroglial modulation of sleep expression and homeostasis via noradrenergic signaling is published in Clocks & Sleep.
A quick discussion of our main findings can be found here.
Our review on the latest research on astroglial contributions to sleep and sleep homeostasis is in press at The FEBS Journal.
The Ingiosi Lab will open in Fall 2022 in the Department of Neuroscience at The Ohio State University!!!
